Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1
نویسندگان
چکیده
منابع مشابه
Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1
Background There are sex differences in the incidence and severity of cardiovascular disease. Although an estrogen-mediated vasculoprotective effect is widely accepted, clinical trial results have been conflicting and the detailed mechanisms are still unclear. Sirtuin 1 (SIRT1), a class III histone deacetylase, may protect against vascular aging and atherosclerosis; however, the effects of estr...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.22546